Current Students
| Student |
Advisor |
Publications |
| Adam Aguiar |
Robert Sikes |
DeGraff DJ, Aguiar AA, Sikes RA. Evidence for IGFBP-2 as a key player in prostate cancer progression and development of osteosclerotic lesions. Am J Translational Res. 2009;1(2):115–130. |
| Melissa Bonner |
Eric Kmiec |
Bonner MA, Naik UP. Cytoplasmic binding partners of the platelet integrin alphaIIb beta3. Front Biosci. 2007;12:2038–2049. |
| Qian (Cynthia) Chen |
Robert Sikes |
DeGraff DJ, Malik M, Chen Q, et al. Hormonal regulation of IGFBP-2 proteolysis is attenuated with progression to androgen insensitivity in the LNCaP progression model. J Cell Physiol. 2007;213(1):261–268. |
| Brian Danysh |
Melinda Duncan |
Danysh BP, Duncan MK. The lens capsule. Exp Eye Res. 2009;88(2):151–164. |
| Danysh BP, Czymmek KJ, Olurin PT, Sivak JG, Duncan MK. Contributions of mouse genetic background and age on anterior lens capsule thickness. Anat Rec (Hoboken). 2008;291(12):1619–1627. |
| Jennifer Illuzzi |
Eric Kmiec |
Illuzzi J, Yerkes S, Parekh-Olmedo H, Kmiec EB. DNA breakage and induction of DNA damage response proteins precede the appearance of visible mutant huntingtin aggregates. J Neurosci Res. 2009;87(3):733–747. |
| John Kostyak |
Ulhas Naik |
Kostyak JC, Naik UP. Megakaryopoiesis: transcriptional insights into megakaryocyte maturation. Front Biosci. 2007;12:2050–2062. |
| Michelle Lucey |
Kenneth van Golen |
Lucey MM, Wang Y, Bustin M, Duncan MK. Differential expression of the HMGN family of chromatin proteins during ocular development. Gene Expr Patterns. 2008;8(6):433–437. |
| Manisha Malik |
Randall Duncan |
DeGraff DJ, Malik M, Chen Q, et al. Hormonal regulation of IGFBP-2 proteolysis is attenuated with progression to androgen insensitivity in the LNCaP progression model. J Cell Physiol. 2007;213(1):261–268. |
| Fayth Miles |
Robert Sikes |
Miles FL, Pruitt FL, van Golen KL, Cooper CR. Stepping out of the flow: capillary extravasation in cancer metastasis. Clin Exp Metastasis. 2008;25(4):305–324. |
| DeGraff DJ, Miles FL, Gomes RR, Sikes RA. Small animal models for the study of cancer in bone. In: Bronner F, Farach-Carson MC, eds. Topics in Bone Biology, Bone and Cancer. Vol. 5.; 2008:181–204. |
| Chung S-W, Miles FL, Sikes RA, Cooper CR, Farach-Carson MC, Ogunnaike BA. Quantitative modeling and analysis of the transforming growth factor beta signaling pathway. Biophys J. 2009;96(5):1733–1750. |
| Deepika Vuppalanchi |
Jeffery Twiss |
Merianda TT, Lin AC, Lam JSY, et al. A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol Cell Neurosci. 2009;40(2):128–142. |
| Yudin D, Hanz S, Yoo S, et al. Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve. Neuron. 2008;59(2):241–252. |
| Chang JH, Vuppalanchi D, van Niekerk E, Trepel JB, Schanen NC, Twiss JL. PC12 cells regulate inducible cyclic AMP (cAMP) element repressor expression to differentially control cAMP response element-dependent transcription in response to nerve growth factor and cAMP. J Neurochem. 2006;99(6):1517–1530. |
| Matthew Weitzman |
Ulhas Naik |
Weitzman M, Bayley EB, Naik UP. Robo4: A guidance receptor that regulates angiogenesis. Cell Adh Migr. 2008;2(4):220–222. |
| Sarah Yerkes |
Eric Kmiec |
Illuzzi J, Yerkes S, Parekh-Olmedo H, Kmiec EB. DNA breakage and induction of DNA damage response proteins precede the appearance of visible mutant huntingtin aggregates. J Neurosci Res. 2009;87(3):733–747. |
Recent Graduates
| Student |
Advisor |
Publications |
| Anissa Brown |
Mary C. Farach-Carson |
Brown AJ, Alicknavitch M, D'Souza SS, et al. Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation. Bone. 2008;43(4):689–699. |
| Farach-Carson MC, Brown AJ, Lynam M, Safran JB, Carson DD. A novel peptide sequence in perlecan domain IV supports cell adhesion, spreading and FAK activation. Matrix Biol. 2008;27(2):150–160. |
| Stephanie Callahan |
Eric Kmiec |
DiMatteo D, Callahan S, Kmiec EB. Genetic conversion of an SMN2 gene to SMN1: a novel approach to the treatment of spinal muscular atrophy. Exp Cell Res. 2008;314(4):878–886. |
| Vesselina Cooke |
Ulhas Naik |
Shao M, Ghosh A, Cooke VG, Naik UP, Martin-DeLeon PA. JAM-A is present in mammalian spermatozoa where it is essential for normal motility. Dev Biol. 2008;313(1):246–255. |
| Xiaoren Chen |
Melinda Duncan |
Chen X, Taube JR, Simirskii VI, Patel TP, Duncan MK. Dual roles for Prox1 in the regulation of the chicken betaB1-crystallin promoter. Invest Ophthalmol Vis Sci. 2008;49(4):1542–1552. |
| David DeGraff |
Robert Sikes |
DeGraff DJ, Miles FL, Gomes RR, Sikes RA. Small animal models for the study of cancer in bone. In: Bronner F, Farach-Carson MC, eds. Topics in Bone Biology, Bone and Cancer. Vol. 5.; 2008:181–204. |
| DeGraff DJ, Malik M, Chen Q, et al. Hormonal regulation of IGFBP-2 proteolysis is attenuated with progression to androgen insensitivity in the LNCaP progression model. J Cell Physiol. 2007;213(1):261–268. |
| Cara Dubyk |
Kenneth van Golen |
van Golen KL, Ying C, Sequeira L, et al. CCL2 induces prostate cancer transendothelial cell migration via activation of the small GTPase Rac. J Cell Biochem. 2008;104(5):1587–1597. |
| Sequeira L, Dubyk CW, Riesenberger TA, Cooper CR, van Golen KL. Rho GTPases in PC-3 prostate cancer cell morphology, invasion and tumor cell diapedesis. Clin Exp Metastasis. 2008;25(5):569–579. |
| Hall CL, Dubyk CW, Riesenberger TA, Shein D, Keller ET, van Golen KL. Type I collagen receptor (alpha2beta1) signaling promotes prostate cancer invasion through RhoC GTPase. Neoplasia. 2008;10(8):797–803. |
| Julia Engstrom |
Eric Kmiec |
Engstrom JU, Kmiec EB. DNA replication, cell cycle progression and the targeted gene repair reaction. Cell Cycle. 2008;7(10):1402–1414. |
| Ferrara L, Engstrom JU, Schwartz T, Parekh-Olmedo H, Kmiec EB. Recovery of cell cycle delay following targeted gene repair by oligonucleotides. DNA Repair (Amst). 2007;6(10):1529–1535. |
| Engstrom JU, Kmiec EB. Manipulation of cell cycle progression can counteract the apparent loss of correction frequency following oligonucleotide-directed gene repair. BMC Mol Biol. 2007;8:9. |
| Ananya Ghosh |
Ulhas Naik |
Shao M, Ghosh A, Cooke VG, Naik UP, Martin-DeLeon PA. JAM-A is present in mammalian spermatozoa where it is essential for normal motility. Dev Biol. 2008;313(1):246–255. |
| Genevieve Griffiths |
Patricia DeLeon |
Griffiths GS, Galileo DS, Reese K, Martin-Deleon PA. Investigating the role of murine epididymosomes and uterosomes in GPI-linked protein transfer to sperm using SPAM1 as a model. Mol Reprod Dev. 2008;75(11):1627–1636. |
| Griffiths GS, Miller KA, Galileo DS, Martin-DeLeon PA. Murine SPAM1 is secreted by the estrous uterus and oviduct in a form that can bind to sperm during capacitation: acquisition enhances hyaluronic acid-binding ability and cumulus dispersal efficiency. Reproduction. 2008;135(3):293–301. |
| Grigorieva A, Griffiths GS, Zhang H, et al. Expression of SPAM1 (PH-20) in the murine kidney is not accompanied by hyaluronidase activity: evidence for potential roles in fluid and water reabsorption. Kidney Blood Press Res. 2007;30(3):145–155. |
| Mohamad Hassanein |
Robert Mason |
Sireesha GV, Mason RW, Hassanein M, et al. Role of cathepsins in blastocyst hatching in the golden hamster. Mol Hum Reprod. 2008;14(6):337–346. |
| Hassanein M, Xue F, Seto CT, Mason RW. Development of a specific inhibitor for the placental protease, cathepsin P. Arch Biochem Biophys. 2007;464(2):288–294. |
| Hassanein M, Korant BD, Lu G, Mason RW. Expression of cathepsin P mRNA, protein and activity in the rat choriocarcinoma cell line, Rcho-1, during giant cell transformation. Placenta. 2007;28(8-9):912–919. |
| Josh Idjadi |
Ron Karlson |
Idjadi JA, Karlson RH. Spatial arrangement of competitors influences coexistence of reef-building corals. Ecology. 2007;88(10):2449–2454. |
| Jill Lynch |
Robert Sikes |
Cooper CR, Graves B, Pruitt F, et al. Novel surface expression of reticulocalbin 1 on bone endothelial cells and human prostate cancer cells is regulated by TNF-alpha. J Cell Biochem. 2008;104(6):2298–2309. |
| Katie Maguire |
Eric Kmiec |
Maguire KK, Kmiec EB. Multiple roles for MSH2 in the repair of a deletion mutation directed by modified single-stranded oligonucleotides. Gene. 2007;386(1-2):107–114. |
| David Manna |
Daniel Simmons |
Wang W, Manna D, Simmons DT. Role of the hydrophilic channels of simian virus 40 T-antigen helicase in DNA replication. J Virol. 2007;81(9):4510–4519. |
| John O'Connor |
Daniel Carson |
O'Connor JC, Farach-Carson MC, Schneider CJ, Carson DD. Coculture with prostate cancer cells alters endoglin expression and attenuates transforming growth factor-beta signaling in reactive bone marrow stromal cells. Mol Cancer Res. 2007;5(6):585–603. |
| Lynn Opdenaker |
Mary C. Farach-Carson |
Opdenaker LM, Farach-Carson MC. Rapamycin selectively reduces the association of transcripts containing complex 5' UTRs with ribosomes in C4-2B prostate cancer cells. J Cell Biochem. 2009;107(3):473–481. |
| Dan Oristian |
Catherine Kirn-Safran |
Oristian DS, Sloofman LG, Zhou X, Wang L, Farach-Carson MC, Kirn-Safran CB. Ribosomal protein L29/HIP deficiency delays osteogenesis and increases fragility of adult bone in mice. J Orthop Res. 2009;27(1):28–35. |
| Freddie Pruitt |
Carlton Cooper |
Cooper CR, Graves B, Pruitt F, et al. Novel surface expression of reticulocalbin 1 on bone endothelial cells and human prostate cancer cells is regulated by TNF-alpha. J Cell Biochem. 2008;104(6):2298–2309. |
| Miles FL, Pruitt FL, van Golen KL, Cooper CR. Stepping out of the flow: capillary extravasation in cancer metastasis. Clin Exp Metastasis. 2008;25(4):305–324. |
| Timothy Schwartz |
Eric Kmiec |
Schwartz TR, Vasta CA, Bauer TL, Parekh-Olmedo H, Kmiec EB. G-rich oligonucleotides alter cell cycle progression and induce apoptosis specifically in OE19 esophageal tumor cells. Oligonucleotides. 2008;18(1):51–63. |
| Ferrara L, Engstrom JU, Schwartz T, Parekh-Olmedo H, Kmiec EB. Recovery of cell cycle delay following targeted gene repair by oligonucleotides. DNA Repair (Amst). 2007;6(10):1529–1535. |
| Schwartz TR, Kmiec EB. Reduction of gene repair by selenomethionine with the use of single-stranded oligonucleotides. BMC Mol Biol. 2007;8:7. |
| Erna van Niekerk |
Jeffery Twiss |
van Niekerk EA, Willis DE, Chang JH, Reumann K, Heise T, Twiss JL. Sumoylation in axons triggers retrograde transport of the RNA-binding protein La. Proc Natl Acad Sci U S A. 2007;104(31):12913–12918.1 |
| Willis DE, van Niekerk EA, Sasaki Y, et al. Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs. J Cell Biol. 2007;178(6):965–980. |
| Wang W, van Niekerk E, Willis DE, Twiss JL. RNA transport and localized protein synthesis in neurological disorders and neural repair. Dev Neurobiol. 2007;67(9):1166–1182. |
| Peng Wang |
Daniel Carson |
Wang P, Julian JA, Carson DD. The MUC1 HMFG1 glycoform is a precursor to the 214D4 glycoform in the human uterine epithelial cell line, HES. Biol Reprod. 2008;78(2):290–298. |
| Weiping Wang |
Daniel Simmons |
Wang W, Manna D, Simmons DT. Role of the hydrophilic channels of simian virus 40 T-antigen helicase in DNA replication. J Virol. 2007;81(9):4510–4519. |
| Wang W, Simmons DT. Simian Virus 40 Large T Antigen Can Specifically Unwind the Central Palindrome at the Origin of DNA Replication. J Virol. 2009;83(7):3312–3322.2 |
