Research Programs

Animal Physiology
Description
Robert E. Akins, Ph.D., F.A.H.A. Development and regulation of cellular organization and function in striated muscle.
Matthew E. R. Butchbach, Ph.D. Mouse models for motor neuron diseases and nerve injury, therapeutic strategies for motor neuron diseases
Melinda K. Duncan, Ph.D., FARVO Eye development.
Randall L. Duncan, Ph.D. Signal transduction of mechanical and hormonal stimulation in the development and maintenance of bone and cartilage.
Jason Gleghorn, Ph.D. Maternal-fetal interactions, drug delivery, and health. Embryonic development.
Salil A. Lachke, Ph.D. Mammalian lens
Sigrid A. Langhans, PhD Pediatric brain tumors - developmental biology and treatment
Gary H. Laverty, Ph.D. Osmoregulation and sensory biology in the unicellular protist Tetrahymena thermophila
Anja Nohe, Ph.D. Role of bone morphogenetic proteins (BMPs) during skeletal development and maintenance.
Robert A. Sikes, Ph.D. Modeling human prostate and breast cancer metastasis in vivo. Hormonal resistance and bone interactions
Shunji Tomatsu MD. PhD. Mouse models for skeletal dysplasias - therapeutic strategies for bone diseases with bone targeting.
Donna Woulfe, Ph.D. Platelet development and roles in hemostasis and thrombosis.
Cancer Biology
Description
Carlton R. Cooper, Ph.D. The role of cell adhesion in prostate cancer preferential metastasis to bone.
Deni S. Galileo, Ph.D. Adhesion molecules that influence glioma brain cancer cell motility in vitro and invasiveness in a chick xenograft model.
Sigrid A. Langhans, PhD Link between obesity and cancer.
Anja Nohe, Ph.D. Role of vitamin D and bone morphogenetic proteins (BMPs) in breast cancer.
Mark Parcells, Ph.D. Cancer vaccines and tumor immunology.
Robert A. Sikes, Ph.D. Human prostate cancer progression. In particular, metastatic cell interaction with nerve and bone marrow stromal cells along with development of novel therapeutic intervention.
Kenneth L. van Golen, Ph.D. Understanding the mechanisms of inflammatory breast cancer metastasis. Understanding the role of RhoC GTPase in aggressive cancers.
Cathy H. Wu, Ph.D. Bioinformatics and computation biology of cancer biology.
Cell and Extracellular Matrix Biology
Description
Robert E. Akins, Ph.D., F.A.H.A. Cell interactions, signaling cascades, and cell migration in tissue engineering and regenerative therapies.
Matthew E. R. Butchbach, Ph.D. Subcellular localization of ribonucleoprotein complexes in neurons, glutamate toxicity in motor neurons
Carlton R. Cooper, Ph.D.
Melinda K. Duncan, Ph.D., FARVO Molecular basis of fibrotic eye disease
Randall L. Duncan, Ph.D. Signal transduction of mechanical and hormonal stimulation in the development and maintenance of bone and cartilage.
Deni S. Galileo, Ph.D. Cell division, death, migration, and differentiation in early development of the vertebrate brain; cancer cell biology and interaction with ECM.
Jason Gleghorn, Ph.D. Multicellular systems, 3D engineered culture platforms, epithelial-stromal cell interactions.
Salil A. Lachke, Ph.D. Lens fiber cell biology
Sigrid A. Langhans, PhD Therapeutic and diagnostic potential of intracellular sodium.
Anja Nohe, Ph.D. Role of bone morphogenetic proteins (BMPs) and vitamin D during mesenchymal stem cell differentiation.
Eleftherios T. Papoutsakis, Ph.D. Blood clotting and platelet function.
Erica M. Selva, Ph.D. Genetic and molecular control of signal transduction during Drosophila development.
Robert A. Sikes, Ph.D. Role of bone marrow stromal cells in prostate cancer metastasis to bone. Role of ion channel accessory proteins in prostate cancer metastasis to bone.
Shunji Tomatsu MD. PhD. Role of extracellular matrix (collagen and glycosaminoglycans) in lysosomal storage disorders.
Kenneth L. van Golen, Ph.D. Understanding the differences between RhoA and RhoC GTPases.
Donna Woulfe, Ph.D. Platelet signal transduction mechanisms.
Cathy H. Wu, Ph.D. Bioinformatics and computation biology of cell and extracellular matrix biology.
Developmental Biology
Description
Robert E. Akins, Ph.D., F.A.H.A. Cardiac morphogenesis and the development of congenital heart malformations.
Melinda K. Duncan, Ph.D., FARVO Eye development.
Randall L. Duncan, Ph.D. Signal transduction of mechanical and hormonal stimulation in the development and maintenance of bone and cartilage.
Deni S. Galileo, Ph.D. Early vertebrate brain development, particularly neuronal migration.
Jason Gleghorn, Ph.D. Lung development, branching morphogenesis, reciprocal signaling, vasculogenesis, role of mechanical forces in organ development.
Salil A. Lachke, Ph.D. Mammalian eye development and disease
Anja Nohe, Ph.D. Mechanisms of skeletal development.
Erica M. Selva, Ph.D. Control of Wnt and hedgehog signaling in Drosophila development.
Robert A. Sikes, Ph.D. Development of the prostate gland.
Jia L. Song, Ph.D. microRNAs regulation of developmental pathways in the early embryo
Ecology and Evolution
Description
E. Fidelma Boyd, Ph.D. Molecular genetics, evolution and pathogenesis of bacteria.
Thomas E. Hanson, Ph.D. Evolution of autotrophy, tundra soil microbial ecology, metaproteomics/genomics.
Gary H. Laverty, Ph.D.
John H. McDonald, Ph.D. Effects of natural selection on nuclear genes.
Mark Parcells, Ph.D. The evolution of herpesvirus virulence.
Douglas Tallamy, Ph.D. Luperine chrysomelid beetle interactions with toxic cucurbitacin triterpenes.
Microbiology and Virology
Description
E. Fidelma Boyd, Ph.D. Molecular genetics, evolution and pathogenesis of bacteria.
Deni S. Galileo, Ph.D. Retroviruses and their use as vectors, including lentiviruses, in vitro and in vivo.
Jason Gleghorn, Ph.D. Viral ecology, phage-bacteria interaction dynamics, microfluidic systems to visualize virus-host relationships.
Thomas E. Hanson, Ph.D. Photosynthetic metabolism, biogeochemistry, applied microbiology.
Calvin L. Keeler, Ph.D. Avian influenza and avian herpesviruses - host-pathogen interactions, vaccines, and diagnostics.
Julia Anne Maresca, Ph.D. Bacterial pigmentation and phototrophy.
Ramona Neunuebel, PhD. Molecular mechanisms of bacterial pathogenesis.
Ramona Neunuebel, PhD. Molecular mechanisms of bacterial pathogenesis.
Eleftherios T. Papoutsakis, Ph.D. Engineering of microbes to produce biofuels.
Mark Parcells, Ph.D. Molecular virology of Marek's disease virus (MDV), an oncogenic herpesvirus of chickens.
Carl Schmidt, Ph.D. Pathogenesis of oncogenic herpes viruses.
K. Eric Wommack, Ph.D. Viruses and their impact on microbial communities.
Cathy H. Wu, Ph.D. Bioinformatics and computation biology of microbiology and virology.
Molecular Biology and Genetics
Description
Robert E. Akins, Ph.D., F.A.H.A. Heterotypic cell interactions in the control of gene expression, multi-cellular organization, and contractile function in striated muscle.
E. Fidelma Boyd, Ph.D. Molecular genetics, evolution and pathogenesis of bacteria.
Matthew E. R. Butchbach, Ph.D. Genetics of motor neuron diseases, generation and characterization of transgenic mouse models of motor neuron diseases
Melinda K. Duncan, Ph.D., FARVO The transcriptional consequences of cell signaling during development.
Deni S. Galileo, Ph.D. Migration, survival, and differentiation of vertebrate brain and of brain tumor cells.
Thomas E. Hanson, Ph.D. Genetic analysis of metabolism, expanding genetic toolkits in novel microbes.
Calvin L. Keeler, Ph.D. Genomic approaches to the study of the innate immune system.
Salil A. Lachke, Ph.D. Mouse developmental genetics
Anja Nohe, Ph.D. Utilizing genetic mouse models of peak bone density to determine the mechanism underlying peak bone mass.
Mark Parcells, Ph.D. Functional analysis of Marek's disease virus (MDV) gene products.
Carl Schmidt, Ph.D. Bioinformatics and avian genomics.
Erica M. Selva, Ph.D. Genetic and molecular control of signal transduction during Drosophila development.
Robert A. Sikes, Ph.D. Mechanisms progression of human prostate cancer to castration resistance. Mechanisms of prostate cancer metastasis to bone.
Shunji Tomatsu MD. PhD. Genetics of skeletal dysplasias - generation and characterization of skeletal dysplasia and lysosomal storage disorder mouse models.
Donna Woulfe, Ph.D. Role of mutations and deletions in genes encoding platelet signaling and membrane surface molecules.
Cathy H. Wu, Ph.D. Bioinformatics and computation biology of molecular biology and genetics.
Science Education
Description
Seung M Hong, Ph.D.