Robert L. Brent, M.D., Ph.D.

Research Interests

Environmental causes of birth defects involving animal studies concerned with environmental exposure to drugs, chemicals, ionizing radiation, microwaves and ultrasound. Specific interest of the laboratory at the present time deal with nutritional requirements of the embryo with emphasis on the folic acid methionine cycle.

Current Projects

Analysis of folic acid metabolic cycle to understand which element of the cycles most vulnerable to perturbations that result in neural tube defects.

Research Group

  • Lynda Fawcett, Ph.D. - Studying the evaluation of the teratogenicity of homocyseine in rat embryos cultured in vitro.
  • Joan Pugarelli, B.S.

Selected Publications

Other Information

Nemours Education and Research Program

Nemours logo University of Delaware logo

An Alliance to Foster Biomedical Research Between the Department of Biological Sciences at the University of Delaware and Nemours Biomedical Research at the Alfred I. duPont Hospital for Children/Nemours Children's Clinic

Head, Clinical and Environmental Teratology Research Lab, A.I. duPont Hospital for Children
Distinguished Professor of Pediatrics, Radiology and Pathology, Thomas Jefferson University

Phone: (302) 651-6880

Fax: (302) 651-6888


Office: Room 308 R/A, A.I. duPont Hospital for Children

Room 308 R/A
A.I. duPont Hospital for Children
Wilmington, DE 19899


  • A.B., M.D., Ph.D., Postdoctoral - University of Rochester