| 223 | Robert E. Akins, Ph.D., F.A.H.A. | <p>Professor<br></p>
<p>Professor, Department of Materials Science & Engineering</p>
<p>Head, Tissue Engineering and Regenerative Medicine Research, A.I. duPont Hospital for Children </p> | (302) 651-6811 | (302) 651-6897 | Robert.Akins@nemours.org | A.I. duPont Hospital for Children | | TERM Lab / 283 ARB Department of Biomedical Research A.I. duPont Hospital for Children Nemours Childrens' Clinic 1600 Rockland Road Wilmington, DE 19803 | <ul>
<li><strong>B.A., Ph.D.</strong> - University of Pennsylvania
</li><li><strong>Postdoctoral</strong> - Thomas Jefferson University
</li><li><strong>Postdoctoral</strong> - A.I. duPont Hospital for Children </li></ul> | | <ul>
<li>Human cardiac tissue engineering
</li><li>Cell and developmental biology of the mammalian heart
</li><li>Advanced electrophoretic techniques for analysis of the proteome
</li><li>Interactions between nerve and muscle in children with cerebral palsy </li></ul> | <ul>
<li><strong>Cardiac tissue engineering</strong> - Mechanisms controlling the assembly of cardiac tissues in vitro.
</li><li><strong>Advanced biomaterials for cardiovascular disease</strong> - Control of cellular pathways with biologically active materials to control cell distribution and function in cardiovascular tissues.
</li><li><strong>Cardiac cell biology</strong> - Heme metabolism in the modulation of myocardial phenotype and cardioprotection.
</li><li><strong>Nerve/muscle interactions</strong> - Maintenance of neuromuscular junctions in children with cerebral palsy. </li></ul> | <ul>
<li><strong>Janet Mendonca, M.S.</strong> - Graduate Student (University of Delaware). Studying the regulation of nerve-muscle interactions in children with cerebral palsy.
</li><li><strong>Karyn Robinson, M.S.</strong> - Senior Research Assistant. Studying the effects of heme oxygenase activity on the organization and function of cultured cardiac cells.
</li><li><strong>Jaimee Militar, B.S.</strong> - Research Assistant. </li></ul> | <ul>
<li>Mizuno J, Morita S, Otsuji M, et al. Half-logistic time constant as inotropic and lusitropic indices for four sequential phases of isometric tension curve with in isolated rabbit and mouse papillary muscles. Int Heart J. 2009:in press.
</li><li>Nie T, Akins REJ, Kiick KL. <a href="http://dx.doi.org/10.1016/j.actbio.2008.12.004">Production of heparin-containing hydrogels for modulating cell responses.</a> Acta Biomater. 2009;5(3):865–875.
</li><li>Barthold JS, McCahan SM, Singh AV, et al. <a href="http://dx.doi.org/10.2164/jandrol.107.003970">Altered expression of muscle- and cytoskeleton-related genes in a rat strain with inherited cryptorchidism.</a> J Androl. 2008;29(3):352–366.
</li><li>Mizuno J, Matsubara H, Mohri S, et al. <a href="http://dx.doi.org/10.1139/y08-001">Half-logistic time constant: a more reliable lusitropic index than monoexponential time constant regardless of temperature in canine left ventricle.</a> Can J Physiol Pharmacol. 2008;86(3):78–87.
</li><li>Rockwood DN, Akins REJ, Parrag IC, Woodhouse KA, Rabolt JF. <a href="http://dx.doi.org/10.1016/j.biomaterials.2008.08.034">Culture on electrospun polyurethane scaffolds decreases atrial natriuretic peptide expression by cardiomyocytes in vitro.</a> Biomaterials. 2008;29(36):4783–4791.
</li><li>Rockwood DN, Chase DB, Akins RE, Rabolt JF. <a href="http://dx.doi.org/10.1016/j.polymer.2008.06.018">Characterization of electrospun poly(N-isopropyl acrylamide) fibers.</a> Polymer. 2008;49(18):4025–4032.
</li><li>Theroux MC, Olivant A, Akins RE. <a href="http://dx.doi.org/10.1111/j.1460-9592.2008.02411.x">C Histomorphology of neuromuscular junction in Duchenne muscular dystrophy.</a> Paediatr Anaesth. 2008;18(3):256–259.
</li><li>Akins RE, Gratton K, Quezada E, Rutter H, Tsuda T, Soteropoulos P. <a href="http://dx.doi.org/10.1089/dna.2006.0543">Gene expression profile of bioreactor-cultured cardiac cells: activation of morphogenetic pathways for tissue engineering.</a> DNA Cell Biol. 2007;26(6):425–434.
</li><li>Mizuno J, Otsuji M, Arita H, et al. <a href="http://dx.doi.org/10.2170/physiolsci.RP013107">Characterization of intracellular Ca2+ transient by the hybrid logistic function in aequorin-injected rabbit and mouse papillary muscles.</a> J Physiol Sci. 2007;57(6):349–359.
</li><li>Singhaus CJ, Utidjian LH, Akins RE, Miller TL, Shaffer TH, Touch SM. <a href="http://dx.doi.org/10.1159/000096968">Growth and development in a heliox incubator environment: a long-term safety study.</a> Neonatology. 2007;91(1):28–35. </li></ul> | | | <img alt="" src="/Images%20Bios/rakins-lg.jpg" style="BORDER:0px solid;" /> | |
